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. Author manuscript; available in PMC: 2010 Jul 6.
Published in final edited form as: Int J Obes (Lond). 2008 Dec;32(Suppl 7):S109–S119. doi: 10.1038/ijo.2008.246

Table 1.

Studies assessing the role of carbohydrate stores on energy intake or body weight

Study Study design (n) Difference in carbohydrate balance or
glycogen store
Difference in EI or BW
Goldberg et al.70 Crossover; 1-day energy restriction by
removing fat or carbohydrate (9)
120±38 kcal day−1 (P=0.09) 86±72 kcal day−1 (NS)
Snitker et al.71 Crossover; 2-day isoenergetic diet, low
or high in carbohydrate (8)
130mmol glucose per kg dry muscle
(46%; P<0.001)
244 kcal day−1 (NS)
Shetty et al.72 Crossover; 2-day isoenergetic
diet high, medium or low in
carbohydrate (6)
1233 kcal 48 h−1 (P<0.05)a 36 kcal 36 h−1 (P=NS)
Stubbs et al.73 Crossover; 1-day isoenergetic diet,
high or low in carbohydrate (9)
576±53 kcal day−1 (P<0.05) 2 kcal day−1 (P=NS)
Pannacciulli et al.74 Cross-sectional; 3-day isoenergetic diet
followed for a 3-day ad libitum food
intake period (112)
−476−533 kcal day−1 (range) Carbohydrate balance
inversely correlated with ad
libitum energy intake
(r=−0.34; P<0.001).
Eckel et al.76 Longitudinal; Measurement of
carbohydrate balance after 15-day
isoenergetic, high-carbohydrate diet
followed by weight gain determination
after 4 years (36)
642±85 kcal day−1 (end of
high-carbohydrate diet)
For each 100 kcal day−1
in carbohydrate balance,
weight gain was 81±37 g
per year lower (P=0.04)

Abbreviations: BW, body weight; EI, energy intake; NS, not significant.

a

Difference between high- and low-carbohydrate diet. Values are mean±s.e.