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. Author manuscript; available in PMC: 2010 Jul 6.
Published in final edited form as: J Thromb Haemost. 2009 Jan 24;7(4):658–664. doi: 10.1111/j.1538-7836.2009.03299.x

Fig. 1. In vitro inhibition of fVIII by MAbs 4A4 and 2-77.

Fig. 1

FVIII was reconstituted into hemophilia A plasma at the indicated concentrations and the inhibition of fVIII by MAbs 4A4 (triangles) or 2-77 (circles) was measured by (A) one-stage coagulation assay and (B) chromogenic assay as described in Methods. The curves represent 4-parameter logistic fits to the data.