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Loss of RpoS decreases the growth-dependent mutation rate of cells overexpressing Pol IV from an exogenous promoter but not of cells not overexpressing Pol IV. The mutation rates were determined by 40-culture fluctuation tests and were calculated by the MSS maximum likelihood method; error bars indicate 95% confidence levels (15, 35). (A) Wild type, PFG266; rpoS::Cm, PFG420. (B) Wild type, FC722; rpoS::Cm, PFG419.
