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. 2010 May 21;192(14):3699–3712. doi: 10.1128/JB.00382-10

FIG. 7.

FIG. 7.

Model of the regulatory role of lQseD and sQseD in EHEC 86-24. In non-O157:H7 EHEC strains, the presence of full-length “long” QseD (lQseD) represses ler and LEE transcription. In the absence of lQseD, an as-yet-unidentified LysR protein (LysR-X) activates LEE transcription. However, in O157:H7 EHEC strains, the presence of truncated “short” QseD (sQseD) represses ler and LEE transcription, presumably through dominant-negative interactions with LysR-X, resulting in incomplete DNA remodeling and transcriptional activation.