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. 2010 May 14;192(14):3809–3821. doi: 10.1128/JB.01672-09

FIG. 1.

FIG. 1.

The pypB gene is part of the tad locus in Y. enterocolitica and encodes the PypB transmembrane transcriptional regulator that is conserved in yersiniae. (A) Genomic organization of the tad locus of Y. enterocolitica. Arrows indicate open reading frames and their directions of transcription. (B) Alignment of PypB of Y. enterocolitica with orthologs from other Yersinia species. The locus tags of the respective genes are indicated (yberc, Y. bercovieri; ykris, Y. kristensenii; yrohd, Y. rohdei; yfred, Y. frederiksenii; yinte, Y. intermedia; ymoll, Y. mollaretii; yruck, Y. ruckeri; yaldo, Y. aldovae; ypsIP31758, Y. pseudotuberculosis IPS31758). Gray bars above the sequence indicate the DNA binding domain and the transmembrane (TM) domain of PypB. (C) Alignment of the Flp protein of Y. enterocolitica (Ye) and Flp-1 of A. actinomycetemcomitans (Aa). The arrow indicates the predicted processing site. The conserved G/(X)4EY and G/(X)3EY motifs are underlined. An asterisk indicates identical residues in all sequences, a colon indicates conserved residues, and a full stop indicates semiconserved residues. Alignments have been generated by using the ClustalW algorithm (22).