FIG. 1.

Changes in body weights, spleen weights, and NMI burdens in the lungs of BALB/c mice and SCID mice infected with 10³ genome copies of NMI. (A) Body weights expressed as a percentage of the initial body weight. Significant differences were found at each time point between 6 and 24 days. (B) Splenomegaly: spleen weights expressed as a percentage of body weight (P < 0.001). (C) NMI burdens in lungs of BALB/c mice and SCID mice infected with 10³ genome copies of NMI (expressed as number of genome copies per lung) determined by RT-PCR (P < 0.001). The data are representative of the results of one of at least two independent experiments performed with five or six mice per group.