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. 2010 May 7;76(13):4216–4232. doi: 10.1128/AEM.00031-10

TABLE 3.

Positively regulated σB-dependent genes present in all four L. monocytogenes lineages

Genea Productb Lineage I
 Lineage II
 Lineage IIIA
 Lineage IIIB
Fold changec Adjusted P valued Fold changec Adjusted P valued Fold changec Adjusted P valued Fold changec Adjusted P valued
lmo0133 Conserved hypothetical protein 4.5 0.0003 5.1 <0.0001 9 <0.0001 14.5 <0.0001
lmo0134 Acetyltransferase, GNAT family 6.9 0.0001 5.6 <0.0001 14.3 <0.0001 7.7 <0.0001
lmo0169 Similar to a glucose uptake protein 5.5 0.0002 3.4 <0.0001 5.1 <0.0001 6.9 <0.0001
lmo0170 Conserved hypothetical protein 3.6 0.0006 3 0.0008 5.6 <0.0001 7.4 <0.0001
lmo0210 Similar to l-lactate dehydrogenase 4.5 <0.0001 2.6 <0.0001 3.8 0.0001 4.6 0.0058
lmo0211 Similar to B. subtilis general stress protein 1.7 0.0335 1.5 0.0001 2.1 0.0021 2.4 <0.0001
lmo0405 Phosphate transporter family protein 2.7 0.0410 1.7 0.0106 2.1 0.0053 2.1 0.0036
lmo0433 Internalin A 3.6 0.0004 3.1 <0.0001 4.8 <0.0001 7 <0.0001
lmo0515 Conserved hypothetical protein 3.3 0.0116 3.4 0.0002 3.5 <0.0001 5.4 <0.0001
lmo0539 Similar to tagatose-1,6-diphosphate aldolase 14.4 <0.0001 7.5 <0.0001 19.5 <0.0001 24.2 <0.0001
lmo0555 Similar to di-tripeptide transporter 7.2 0.0002 4.1 <0.0001 7.1 <0.0001 9.3 <0.0001
lmo0593 Similar to transport proteins (formate) 6 0.0032 5.7 <0.0001 9 0.0003 18.2 <0.0001
lmo0596 Similar to unknown proteins 14.2 0.0001 22.7 <0.0001 33.8 <0.0001 36 <0.0001
lmo0602 Weakly similar to transcription regulator 2.6 0.0023 3.7 <0.0001 2.8 0.0003 2.5 0.0121
lmo0610 Similar to internalin proteins, putative peptidoglycan-bound protein (LPXTG motif) 1.9 0.0380 3.7 <0.0001 5.5 <0.0001 8.2 <0.0001
lmo0642 Putative membrane protein 3.4 0.0028 2 0.0002 2 0.0029 3.1 0.0005
lmo0655 Similar to phosphoprotein phosphatases 4.4 <0.0001 2.9 <0.0001 2.5 0.0014 3.1 0.0007
lmo0722 Similar to pyruvate oxidase 4.6 0.0002 5.4 <0.0001 8.8 <0.0001 3.8 0.0070
lmo0781 Similar to mannose-specific PTS component IID 10 <0.0001 15.6 <0.0001 18.2 <0.0001 25.4 <0.0001
lmo0782 Similar to mannose-specific PTS component IIC 12.9 <0.0001 13.5 <0.0001 20.3 <0.0001 22 <0.0001
lmo0783 Similar to mannose-specific PTS component IIB 6.4 <0.0001 12 <0.0001 14.8 <0.0001 18 <0.0001
lmo0784 PTS system, IIAB component, authentic frameshift 2 0.0341 5.7 <0.0001 5.5 <0.0001 6.4 <0.0001
lmo0794 Similar to B. subtilis YwnB protein 6.1 0.0007 12.8 <0.0001 10.3 <0.0001 25.4 <0.0001
lmo0796 Conserved hypothetical protein 1.9 0.0029 4 <0.0001 8.3 <0.0001 12.3 <0.0001
lmo0880 LysM domain protein 7.4 <0.0001 6.7 <0.0001 16.4 <0.0001 6.8 0.0006
lmo0896 Indirect negative regulation of σB-dependent gene expression (serine phosphatase) 1.5 0.0244 2.3 <0.0001 1.7 0.0197 2.7 0.0017
lmo0911 Unknown 2.1 0.0152 2.1 <0.0001 9.2 <0.0001 1.8 0.0200
lmo0913 Succinate semialdehyde dehydrogenase 6.6 <0.0001 13.4 <0.0001 16 <0.0001 22.3 <0.0001
lmo0937 Unknown 6.4 <0.0001 10.4 <0.0001 16.2 <0.0001 18.9 <0.0001
lmo0953 Unknown 3.2 0.0156 6.5 <0.0001 12 <0.0001 16.3 <0.0001
lmo0956 Similar to N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) 2.6 0.0073 2.1 <0.0001 4.4 <0.0001 4.3 <0.0001
lmo0957 Glucosamine-6-phosphate isomerase 2.3 0.0006 1.6 0.0027 3.1 0.0027 2.4 0.0441
lmo0994 Unknown 24.4 <0.0001 14.1 <0.0001 54.2 <0.0001 79.2 <0.0001
lmo1140 Unknown 4 0.0084 3.5 <0.0001 4.9 0.0001 4.9 <0.0001
lmo1241 Conserved hypothetical protein 2.7 0.0012 2.2 0.0002 4.2 <0.0001 5 <0.0001
lmo1295 Similar to host factor 1 protein 1.8 0.0120 3.4 <0.0001 5.4 <0.0001 8 <0.0001
lmo1375 Peptidase, M20/M25/M40 family 2.4 0.0168 3 <0.0001 2.4 0.0025 2.1 0.0381
lmo1425 Similar to betaine-carnitine-choline ABC transporter (membrane protein) 1.9 0.0062 3.4 <0.0001 3.5 <0.0001 4.7 <0.0001
lmo1428 Similar to glycine betaine-carnitine-choline ABC transporter (ATP-binding protein) 2.2 0.0008 2.9 <0.0001 2.7 0.0001 3.5 0.0004
lmo1433 Pyridine nucleotide disulfide oxidoreductase family protein 4.7 0.0006 4.2 <0.0001 3 0.0378 3.7 0.0309
lmo1602 Similar to unknown proteins 4.2 <0.0001 4.6 <0.0001 1.7 0.0417 2.7 <0.0001
lmo1605 UDP-N-acetylmuramate-alanine ligase 7.4 0.0001 2.2 <0.0001 2.4 0.0047 2.8 <0.0001
lmo1606 FtsK/SpoIIIE family protein 9.1 <0.0001 5.6 <0.0001 3.5 <0.0001 4.1 <0.0001
lmo1694 Similar to CDP-abequose synthase 8 <0.0001 8 <0.0001 26.2 <0.0001 1.8 0.0162
lmo1799 Putative peptidoglycan-bound protein (LPXTG motif) 2.8 0.0017 1.7 0.0002 4.8 <0.0001 4.7 <0.0001
lmo2085 Cell wall surface anchor family protein 11 <0.0001 12.2 <0.0001 14.1 0.0007 16.8 0.0067
lmo2130 Similar to unknown protein 2.1 0.0112 2.6 <0.0001 1.9 0.0104 2.3 0.0006
lmo2191 Similar to unknown proteins 2.2 0.0066 3 <0.0001 2.3 <0.0001 2.3 <0.0001
lmo2269 Unknown 4.3 0.0096 5.7 <0.0001 5.6 <0.0001 6.2 <0.0001
lmo2391 Conserved hypothetical protein similar to B. subtilis YhfK protein 6.2 <0.0001 9.1 <0.0001 21.6 <0.0001 28.5 <0.0001
lmo2434 Glutamate decarboxylase gamma 3.2 0.0193 2.7 <0.0001 4 0.0097 3.8 <0.0001
lmo2454 Unknown 3.6 0.0003 4.6 <0.0001 6.6 <0.0001 8.2 <0.0001
lmo2463 Similar to transport protein 3 0.0426 3.9 <0.0001 6.2 <0.0001 4.3 0.0266
lmo2485 PspC domain protein, truncated 1.9 0.0113 4.4 <0.0001 1.8 0.0006 2 0.0021
lmo2570 Putative membrane protein 5.5 <0.0001 4.5 <0.0001 7.3 <0.0001 8.9 <0.0001
lmo2571 Similar to nicotinamidase 4.4 <0.0001 5.8 <0.0001 7.3 <0.0001 8.3 <0.0001
lmo2572 Similar to chain A, dihydrofolate reductase 4.4 0.0002 1.6 0.0018 7.5 <0.0001 3.5 <0.0001
lmo2573 Alcohol dehydrogenase, zinc dependent 3.4 0.0002 4.6 <0.0001 5.6 <0.0001 7.5 <0.0001
lmo2673 Conserved hypothetical protein 6.9 0.0009 9.7 <0.0001 26 <0.0001 37.2 <0.0001
lmo2674 Similar to ribose-5-phosphate epimerase 9.8 <0.0001 3.8 <0.0001 10.1 <0.0001 13.7 <0.0001
lmo2724 Similar to unknown proteins 2.8 0.0030 2.9 <0.0001 4.7 <0.0001 4.9 <0.0001
lmo2748 Similar to B. subtilis stress protein YdaG 11.6 <0.0001 10 <0.0001 15.3 <0.0001 5.1 0.0063
lmo-f2365_0703 Conserved hypothetical protein 2.2 0.0277 3.3 <0.0001 2.2 0.0038 2.4 0.0186
a

Gene names are based on the L. monocytogenes EGDe locus.

b

Common names of products are based on the EGDe annotation.

c

Changes in the transcript level in the parent strain compared to the transcript level in the ΔsigB strain. A ≥1.5-fold change was considered significant.

d

An adjusted P value of <0.05 was considered significant.