TABLE 4.

JCVI role categories with over- or underrepresentation for σ^B-dependent genes

JCVI role categorya	No. of annotated genes	No. of σB-dependent genesb	Fisher's exact test P valuec	Odds ratiod
Cellular processes	165	35	0.0463	1.5
Energy metabolism	380	103	<0.0001	2.3
DNA metabolism	102	8	0.0263	0.5
Regulatory functions	226	24	0.0361	0.6
Unknown function	109	9	0.0312	0.5

^aJCVI L. monocytogenes EGD-e role categories.

^bNumber of σ^B-dependent genes in all lineage representatives for each role category.

^cFisher's exact test was used to identify significant associations between σ^B-dependent genes and the total number of genes in a role category; two-sided P values of <0.05 were considered significant.

^dOdds ratios were calculated to characterize significant associations between σ^B-dependent genes and role category.