Scheme of glucose oxidation of G. oxydans. Gn, glucono-δ-lactonases; Ga-2-DH, membrane-bound gluconate 2-dehydrogenase; Ga-5-DH, membrane-bound gluconate 5-dehydrogenase (= SldAB); 2-KGDH, membrane-bound 2-ketogluconate dehydrogenase; GK, glucose kinase; Gnt K, gluconokinase; Zwf, glucose-6-phosphate dehydrogenase; GntV, 6-phophoglucono-δ-lactonase; Gnd, 6-phosphogluconate dehydrogenase; Edd, 6-phosphogluconate dehydratase. The GOX numbers refer to the analogous genes/enzymes in G. oxydans 621H. For the 2-KGDH-encoding gene in G. oxydans N44-1, no analog exists in G. oxydans 621H.