TABLE 3.
Other microorganisms recovered from sputum samples from patients colonized by Geosmithia argillacea
| Patient | No. of sputum samples positive for G. argillacea (duration [mo] of chronic colonization) | Microorganisms colonizing the airways (beginning or period of colonization)a |
Antifungal drug(s) (beginning or period of treatment)b | |
|---|---|---|---|---|
| Bacteria | Fungi | |||
| Ac | 7 (14) | Staphylococcus aureus (September 2007 →) | Aspergillus fumigatus (2001-October 2006, September 2007 →), Candida albicans (2005 →) Aspergillus flavus (September 2007 →) | ITZ (February 2006-July 2007) |
| B | 3 | Staphylococcus aureus (January 2006 →) Pseudomonas aeruginosad (March 2007 →) | Candida albicans (2001 →) Candida parapsilosis (2002-October 2006) Aspergillus fumigatus (2005-November 2006, April 2007 →) Aspergillus flavus (2005-November 2006) Scedosporium apiospermum (October 2006 →) | ITZ (February 2007 →) |
| C | 2 | Pseudomonas aeruginosad (1996-1998) Staphylococcus aureus (1997 →) | Aspergillus fumigatus (1997-August 1999, October 1999 →) Aspergillus terreus (1998-March 1999, November 1999 →) | ITZ (September 1999-February 2000) |
| D | 2 | Staphylococcus aureus (2002 →) | Aspergillus fumigatus (2003 →) Aspergillus terreus (2006 →) Exophiala dermatitidis (2006 →) Aspergillus flavus (2007 →) | ITZ (July 2003-February 2004, September 2004 →) |
| Ee | 8 (10) | Staphylococcus aureus (2004 →) Pseudomonas aeruginosa (2002 →) | Aspergillus fumigatus (2001-October 2007, September 2008 →) Candida albicans (2007 →) | VCZ (June 2004-July 2006) ITZ (July 2006-January 2008) PCZ (February 2008-June 2008, September 2008-May 2009) |
| F | 5 (19) | Staphylococcus aureus (1996 →) Pseudomonas aeruginosa (2003 →) | Aspergillus fumigatus (2003-February 2008) Aspergillus flavus (2004-2005) | ITZ (August 2007-February 2008, June 2008 →) |
| G | 6 (23) | Staphylococcus aureus (2004 →) Pseudomonas aeruginosad (2004 →) | Candida albicans (July 2005 →) Aspergillus fumigatus (2004-November 2005, April 2006-December 2006) | VCZ (February 2007-March 2007) PCZ (March 2007-November 2007) ITZ (January 2008-February 2008) PCZ (February 2008-April 2008, November 2008-October 2009, November 2009 →) |
| H | 3 | Pseudomonas aeruginosa (2000 →) | Aspergillus fumigatus (2000-2004, February 2009 →) | ITZ (December 2004) CS (March 2009) ITZ (March 2009-December 2009) |
a
Arrows indicate the continuation of the airway colonization at the date of last isolation of G. argillacea. Unless otherwise indicated, all microorganisms recovered from sputum samples were responsible for chronic colonization of the patient (defined as at least two isolations over a period of 6 months).
b
Arrows indicate the continuation of the antifungal treatment at the date of last isolation of G. argillacea. CS, caspofungin; ITZ, itraconazole; PCZ, posaconazole; VCZ, voriconazole.
c
Patients A was infected by a Mycobacterium sp. in September 2007.
d
Not responsible for chronic colonization.
e
Patient E was infected by a Mycobacterium sp. in 1994.