TABLE 1.
Distribution of phylogenetic groups and virulence factors among ABU and CA-ABU E. coli isolates
| Phylogenetic group, virulence gene, or phenotype | All strains |
Ampicillin resistance |
Cephalothin resistance |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. (%) of strains |
Pb | No. (%) of ABU strains |
P for ABU strains | No. (%) of CA-ABU strains |
P for CA-ABU strains | No. (%) of ABU strains |
P for ABU strains | No. (%) of CA-ABU strains |
P for CA-ABU strains | ||||||
| ABU (n = 88) | CA-ABU (n = 88) | Susceptible (n = 45) | Resistant (n = 43) | Susceptible (n = 44) | Resistant (n = 44) | Susceptible (n = 40) | Resistant (n = 48) | Susceptible (n = 36) | Resistant (n = 52) | ||||||
| Phylogenetic group | |||||||||||||||
| A | 7 (8) | 8 (9) | NS | 3 (7) | 4 (9) | NS | 3 (7) | 5 (11) | NS | 1 (3) | 6 (13) | NS | 4 (11) | 4 (8) | NS |
| B1 | 5 (6) | 3 (3) | NS | 3 (7) | 2 (5) | NS | 3 (7) | 0 (0) | NS | 2 (5) | 3 (6) | NS | 2 (6) | 1 (2) | NS |
| B2 | 60 (68) | 60 (68) | NS | 33 (73) | 27 (63) | NS | 28 (64) | 32 (73) | NS | 35 (88) | 25 (52) | <0.001 | 22 (61) | 38 (73) | NS |
| D | 16 (18) | 17 (19) | NS | 6 (13) | 10 (23) | NS | 10 (23) | 7 (16) | NS | 2 (5) | 14 (29) | 0.005 | 8 (22) | 9 (17) | NS |
| Virulence gene | |||||||||||||||
| fimH | 86 (98) | 86 (98) | NS | 45 (100) | 41 (95) | NS | 43 (98) | 43 (98) | NS | 40 (100) | 46 (96) | NS | 35 (97) | 51 (98) | NS |
| papG I | 3 (3) | 0 (0) | NS | 1 (2) | 2 (5) | NS | 0 (0) | 0 (0) | NS | 0 (0) | 3 (6) | NS | 0 (0) | 0 (0) | NS |
| papG II | 16 (18) | 26 (30) | NS | 8 (18) | 8 (19) | NS | 6 (14) | 20 (45) | 0.001 | 8 (20) | 8 (17) | NS | 7 (19) | 19 (37) | NS |
| papG III | 21 (24) | 17 (19) | NS | 13 (29) | 8 (19) | NS | 8 (18) | 9 (20) | NS | 15 (38) | 6 (13) | 0.006 | 9 (25) | 8 (15) | NS |
| papG (all alleles) | 37 (42) | 38 (43) | NS | 21 (47) | 16 (37) | NS | 14 (32) | 24 (55) | 0.031 | 22 (55) | 15 (31) | 0.025 | 15 (42) | 23 (44) | NS |
| flu | 51 (58) | 55 (63) | NS | 25 (56) | 26 (60) | NS | 21 (48) | 34 (77) | 0.004 | 27 (68) | 24 (50) | NS | 23 (64) | 32 (62) | NS |
| focG | 14 (16) | 20 (23) | NS | 9 (20) | 5 (12) | NS | 9 (20) | 11 (25) | NS | 11 (28) | 3 (6) | 0.009 | 11 (31) | 9 (17) | NS |
| sfaS | 8 (9) | 7 (8) | NS | 4 (9) | 4 (9) | NS | 5 (11) | 2 (5) | NS | 6 (15) | 2 (4) | NS | 2 (6) | 5 (10) | NS |
| afa/draBC | 7 (8) | 7 (8) | NS | 6 (13) | 1 (2) | NS | 2 (5) | 5 (11) | NS | 4 (10) | 3 (6) | NS | 4 (11) | 3 (6) | NS |
| mrkB | 1 (1) | 3 (3) | NS | 0 (0) | 1 (2) | NS | 2 (5) | 1 (2) | NS | 1 (3) | 0 (0) | NS | 2 (6) | 1 (2) | NS |
| hlyA | 17 (19) | 24 (27) | NS | 12 (27) | 5 (12) | NS | 12 (27) | 12 (27) | NS | 13 (33) | 4 (8) | 0.006 | 11 (31) | 13 (25) | NS |
| cnf1 | 24 (27) | 23 (26) | NS | 12 (27) | 12 (28) | NS | 11 (25) | 12 (27) | NS | 15 (38) | 9 (19) | 0.049 | 10 (28) | 13 (25) | NS |
| fyuA | 69 (78) | 73 (83) | NS | 34 (76) | 35 (81) | NS | 34 (77) | 39 (89) | NS | 31 (78) | 38 (79) | NS | 26 (72) | 47 (90) | 0.026 |
| iutA | 31 (35) | 43 (49) | NS | 10 (22) | 21 (49) | 0.009 | 13 (30) | 30 (68) | <0.001 | 15 (38) | 16 (33) | NS | 14 (39) | 29 (56) | NS |
| iroN | 44 (50) | 37 (42) | NS | 27 (60) | 17 (40) | NS | 17 (39) | 20 (45) | NS | 30 (75) | 14 (29) | <0.001 | 16 (44) | 21 (40) | NS |
| kpsMT II | 45 (51) | 63 (72) | 0.005 | 18 (40) | 27 (63) | 0.033 | 29 (66) | 34 (77) | NS | 18 (45) | 27 (56) | NS | 20 (56) | 43 (83) | 0.006 |
| kpsMT III | 1 (1) | 4 (5) | NS | 0 (0) | 1 (2) | NS | 2 (5) | 2 (5) | NS | 0 (0) | 1 (2) | NS | 2 (6) | 2 (4) | NS |
| kpsMT K1 | 11 (13) | 28 (32) | 0.002 | 7 (16) | 4 (9) | NS | 16 (36) | 12 (27) | NS | 5 (13) | 6 (13) | NS | 9 (25) | 19 (37) | NS |
| kpsMT K5 | 24 (27) | 34 (39) | NS | 9 (20) | 15 (35) | NS | 12 (27) | 22 (50) | 0.029 | 10 (25) | 14 (29) | NS | 11 (31) | 23 (44) | NS |
| Virulence gene score, median | 5 | 6 | NS | 5 | 5 | NS | 4 | 6 | 0.017 | 7 | 4 | 0.004 | 6 | 6 | NS |
| Phenotype | |||||||||||||||
| Yeast agglut.a | 82 (93) | 81 (92) | NS | 43 (96) | 39 (91) | NS | 41 (93) | 40 (91) | NS | 37 (93) | 45 (94) | NS | 33 (92) | 48 (92) | NS |
| MRHA | 30 (34) | 13 (15) | 0.003 | 16 (36) | 14 (33) | NS | 7 (16) | 6 (14) | NS | 18 (45) | 12 (25) | 0.049 | 9 (25) | 4 (8) | 0.033 |
| Hemolysis | 18 (20) | 16 (18) | NS | 13 (29) | 5 (12) | 0.045 | 8 (18) | 8 (18) | NS | 14 (35) | 4 (8) | 0.003 | 8 (22) | 8 (15) | NS |
| Motility | 60 (68) | 63 (72) | NS | 30 (67) | 30 (70) | NS | 34 (77) | 29 (66) | NS | 25 (63) | 35 (73) | NS | 24 (67) | 39 (75) | NS |
| Biofilm | 52 (59) | 42 (48) | NS | 26 (58) | 26 (60) | NS | 27 (61) | 15 (34) | 0.010 | 24 (60) | 28 (58) | NS | 20 (56) | 22 (42) | NS |
a
agglut., agglutination.
b
Only significant P values (P < 0.05) have been shown; nonsignificant values are labeled NS.