TABLE 1.
Characteristic | Value/description for subject: |
|||||||
---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
No. of sputum samples | 79 | 73 | 68 | 13 | 11 | 26 | 78 | 91 |
No. of positive samples (%) | 29 (36.7) | 1 (1.4) | 11 (16.8) | 9 (69) | 15 (73.3) | 2 (7.7) | 1 (1.3) | 29 (31.9) |
Age at first isolation (yr) | 26 | 24 | 27 | 21 | 6 | 19 | 8 | 14 |
CF genotype | DF508 DF508 | DF508 DF508 | DF508 2184delA | DF508 Q493X | DF508 DF508 | DF508 DF508 | DF508 1717-1(G>T) | DF508 DF508 |
FEV1 at first isolation (% predicted)c | 15 | 82 | 17 | 55 | 73 | 58 | 58 | 27 |
Other organismsa | Af, As, Mv | Af, Sa, MRSA, Pa, Mc | Bccm | Af, Sa, Pa | Af, Sm | Af, Pa, Mc | Bccc, Pa, Af, Ma | Af, Psp, Pa, Ps, Ax, As, Mv |
Any associated decline? | No | No | No | No | No | No | No | No |
Comment(s)b | Listed for lung transplantation prior to isolation | Two episodes of hemoptysis within 2 months of isolation, not; to be related | Subsequently listed for lung transplantation | CT chest shows plugged dilated bronchus and nodularity in right upper lobe | Listed for lung transplantation prior to isolation thought has subsequently undergone transplantation |
Af, Aspergillus fumigatus; As, Alcaligenes sp.; Ma, Mycobacterium abscessus; Sa, Staphylococcus aureus; MRSA, methicillin-resistant S. aureus; Pa, Pseudomonas aeruginosa; Mc, Mycobacterium chelonae; Bccm, Burkholderia cepacia complex sp. B. multivorans; Sm, Streptococcus milleri; Bccc, Burkholderia cepacia complex sp. B. cenocepacia; Psp, Paecilomyces sp.; Ps, Pseudoxanthomonas sp.; Ax, Achromobacter xylosoxidans; Mv, Mycobacterium avium; Hf, Haemophilus influenzae.
CT, computed tomography.
FEVI, forced expiratory volume in 1 s.