FIG. 4.

Outcome of VRE colonization in patients receiving Lcr35 (solid arrow, n = 6) versus placebo (dashed arrow, n = 2) for a 5-week period (W1 to W5). VRE was detected in patient stools from W1 to W11; black bars, positive VRE cultures; gray bars, negative VRE cultures. Nine VRE-positive patients were recruited. One patient died 2 days after inclusion and was excluded from the analysis. Of the eight remaining patients, six received Lcr35 and two received placebos. Patients 1 and 2 completed the treatment with placebo but stopped the study after W7. Patient 5 stopped the treatment with Lcr35 after 3 weeks. The Charlson index of comorbidity was 3 to 4 for two patients and higher than 5 for six of them.