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Curing of cells coexpressing Ssa1 or Sse1. Curing was done as described in the legend for Fig. 1, using cells carrying plasmids with HSP104 (104), SSA1 (A1), and SSE1 (E1) or the corresponding empty vectors (ev). Western analysis probing for the chaperones indicated on the left was done using cultures grown for four generations. Numbers below the image indicate rates of prion curing (%[psi−] per generation) for the strains labeled directly above.
