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Ub effects on curing of [PSI+] by Hsp104 overexpression. Rates of curing of cultures grown for four to six generations were determined as described in the legend for Fig. 1. Strains (indicated at bottom) carry empty vector (−) or the same plasmid with UBI4 (+), which encodes Ub. Values are averages of the results for three independent experiments ± standard deviation. Student's t test values are as follows: wild type, P = 0.0014; others, P = 0.1.
