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. 2010 May 19;84(15):7703–7712. doi: 10.1128/JVI.02560-09

FIG. 9.

FIG. 9.

ERK1/2 regulate the promoter activity of CCL2 induced by SARS-CoV VLPs. At 2 days posttransfection of A549 cells with pGLM-PRM plasmid, the cells were treated with the inhibitor PD98059 (PD) or SP600125 (SP) for 1 h prior to a further incubation with SARS-CoV VLPs for 24 h. A luciferase reporter assay was performed. The results shown represent the means plus standard deviations (error bars) from four independent experiments. DMSO, dimethyl sulfoxide.