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VN/1203 infection is more pathogenic than 1918 infection in a mouse model of infection. (A) Mortality data from a total of 12 mice (6 mice/virus). (B) Viral dissemination data from a total of 12 mice (3 mice/virus/time point). d, day(s). (C) Lung virus titer data from a total of 18 wild-type mice (3 mice/virus/time point) infected with 1918 or VN/1203 virus. The limit of detection in this assay is indicated by black and grey bars at 1.2 × 101 EID50/ml.
