TABLE 6.
Cross-reactivity of postinfection mouse sera against selected H2 viruses in a neutralization assaya
Virus | Titer of mouse serum in neutralization assay |
||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Jap/57b | Kras/59b | AA/6/ 60 | Berlin/64 | Berk/68 | pin/Prai/ 76 | mal/NY/ 78b | mal/Pot/ 83b | ck/ NY/91 | dk/ Hok/01 | mal/ Alb/02 | tern/ Aus/04 | dk/ Hok/05 | dk/ Mng/06 | sw/MO/ 06b | |
Jap/57 | 320 | 32 | 20 | 226 | 40 | 28 | 202 | 202 | 113 | 80 | 226 | 10 | 10 | 20 | 381 |
Kras/59 | 254 | 80 | 20 | 40 | 10 | 32 | 254 | 226 | 10 | 80 | 101 | 40 | 320 | 254 | 453 |
AA/6/60 | 101 | 80 | 50 | 113 | 453 | 10 | 40 | 32 | 10 | 10 | 10 | 16 | 40 | 10 | 16 |
Berlin/64 | 32 | 320 | 16 | 202 | 40 | 10 | 10 | 16 | 20 | 16 | 28 | 28 | 10 | 57 | 10 |
Berk/68 | 20 | 320 | 10 | 226 | 453 | 10 | 10 | 10 | 10 | 10 | 16 | 10 | 10 | 25 | 10 |
pin/Prai/76 | 160 | 80 | 10 | 40 | 10 | 57 | 113 | 63 | 10 | 57 | 80 | 10 | 320 | 254 | 453 |
mal/NY/78 | 202 | 320 | 10 | 10 | 10 | 20 | 226 | 127 | 10 | 80 | 254 | 10 | 453 | 32 | 202 |
mal/Pots/83 | 254 | 160 | 10 | 16 | 10 | 25 | 202 | 113 | 10 | 50 | 50 | 10 | 202 | 63 | 226 |
ck/NY/91 | 127 | 127 | 10 | 28 | 10 | 40 | 160 | 113 | 226 | 50 | 226 | 20 | 226 | 63 | 806 |
dk/Hok/01 | 160 | 127 | 10 | 32 | 10 | 16 | 202 | 113 | 101 | 113 | 101 | 10 | 135 | 63 | 640 |
mal/Alb/02 | 202 | 63 | 10 | 16 | 10 | 28 | 160 | 101 | 10 | 32 | 254 | 10 | 67 | 127 | 508 |
tern/Aus/04 | 101 | 63 | 10 | 16 | 10 | 10 | 63 | 32 | 10 | 20 | 63 | 113 | 67 | 127 | 50 |
dk/Hok/05 | 805 | 113 | 25 | 127 | 16 | 50 | 453 | 113 | 16 | 202 | 226 | 226 | 160 | 226 | 1,280 |
dk/Mng/06 | 320 | 320 | 10 | 63 | 20 | 50 | 226 | 160 | 202 | 101 | 160 | 10 | 320 | 2,032 | 640 |
sw/MO/06 | 160 | 127 | 10 | 16 | 16 | 25 | 127 | 101 | 28 | 101 | 101 | 10 | 160 | 113 | 806 |
Homologous titers are in bold; 4-fold-or-greater differences in titer are underlined. The lower limit of detection was assigned a value of 10. Mouse antisera were generated against the viruses indicated.
Antiserum with cross-neutralizing antibody to the greatest number of heterologous H2 subtype influenza viruses.