TABLE 1.

Role of HRV in lung diseases^a

Clinical syndrome	Population cohort	% virus-infected subjects		% HRV-infected subjectsb		References
		Sick	Well	Sick	Well
Acute illness
Bronchiolitis	Outpatient with wheezing aged <2 years	66-68	25-31	33-45	11-26	21, 58, 66
	Hospitalized or emergency department patient aged <2 years	86-93		10-30		7, 42, 72
Pneumonia	Hospitalized childrenc	55-65		24-45		48, 61, 112
	Immunocompromised adultsc	17-19		4-8		20, 39
Exacerbation of chronic lung disease
Asthma	Outpatient children	62-81	12-41	52-54	12-28	44, 47
	Hospitalized children	61-63	18-23	48-57	2-19	33, 51
	Outpatient adults	44-76	3-13	18-48	0-13	2, 32, 52, 85
	Hospitalized adults	26-48	18	10-35	4	29, 108
COPD	Older adults	22-64	12-19	3-36	0-4	54, 77, 96, 100, 108
Cystic fibrosis	Children	28		16		105

^aStudies in the table are limited to those using molecular techniques for detection of HRV. Some of the studies mentioned in the article used diagnostic techniques that did not differentiate between HRV and enteroviruses and reported detection rates for picornaviruses. Some studies did not include control data for virus detection in well children.

^bData for infections with HRV as a single viral pathogen.

^cBacterial and viral pathogens codetected in some infections.