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Combinations of replicon and Δ26S helper RNAs used to generate VRP for mouse study
| Group identifier | Combination with: |
||
|---|---|---|---|
| Replicon RNA | Capsid helper | GP helper | |
| Wild type | pERK/383/EV71/HA | dHcap6-m1 | dHgp6-m1 |
| Std Rep + miHelpers | pERK/383/EV71/HA | dHcap6-m1 3′ RC1-6-plus | dHgp6-m1 3′ RC1-6-plus |
| miRep + miHelpers | pERK/383/EV71/HA 3′ RC1-6-plus | dHcap6-m1 3′ RC1-6-plus | dHgp6-m1 3′ RC1-6-plus |
