Table 3.
Expression proteomics of SE2472 upon exposure to H2O2, categorized by protein functions.
| Description | Change |
|---|---|
| Glycolysis/Gluconeogenesis | |
| Enolase | 23 ± 4% |
| Fructose-1-phosphate kinase | 35 ± 3% |
| Fructose-bisphosphate aldolase | 52 ± 7% |
| Phosphoenolpyruvate carboxykinase | 330 ± 40% |
| Phosphoglycerate kinase | 20 ± 3% |
| Phosphoglyceromutase | -40 ± 10% |
| Phosphopyruvate hydratase | 12 ± 2% |
| Pyruvate kinase I | 87 ± 12% |
| TCA Cycle | |
| Aconitate hydratase 2 | 18 ± 2% |
| Bifunctional aconitate hydratase | 25 ± 5% |
| Citrate synthase | 42 ± 5% |
| Malate dehydrogenase | 36 ± 6% |
| Transcription/Translation | |
| Elongation factor G | 9 ± 2% |
| Elongation factor Ts | 21 ± 4% |
| Elongation factor Tu | 0% |
| Endonuclease IV | 0% |
| RNA polymerase sigma factor rpoS | 13 ± 2% |
| DNA Replication/Repair | |
| ATP-dependent helicase | 20 ± 3% |
| DNA adenine methylase | 26 ± 3% |
| DNA mismatch repair protein mutL | 41 ± 3% |
| Single-strand DNA-binding protein | 19 ± 2% |
| Uracil-DNA glycosylase | 27 ± 2% |
| Type III Secretion System | |
| Secretory Effector Protein (SipA) | 0% |
| Translocation Machinery Component (SipC) | 301 ± 30% |
| Secretory Effector Protein (SopB) | -55% ± 7% |
| Pentose Phosphate Pathway | |
| Deoxyribose-phosphate aldolase | 0% |
| Glucose-6-phosphate 1-dehydrogenase | 0% |
| Phosphopentomutase | 0% |
| 2-dehydro-3-deoxygluconokinase | 9 ± 2% |
| Nucleotide synthesis and metabolism | |
| Amidophosphoribosyltransferase | 10 ± 4% |
| Thymidine phosphorylase | -9 ± 2% |
| Uridine phosphorylase | 11 ± 5% |
| Amino acid synthesis and metabolism | |
| Shikimate dehydrogenase | 12 ± 3% |
| Succinylornithine transaminase | 41 ± 7% |
| Tryptophan synthase | 37 ± 9% |
Representative proteins are shown.