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. 2010 Jul 6;4(7):e733. doi: 10.1371/journal.pntd.0000733

Figure 2. Circulating Total and CRP-specific IgM and IgG after T. cruzi infection.

Figure 2

A, Infected mice (n = 5 per group) were bled at multiple time-points post-infection and their pooled sera analyzed for total IgM (top) and total IgG (bottom), with triplicate repeats for each time-point. B, Pooled sera were analyzed for CRP-specific IgM and CRP-specific IgG by ELISA in duplicate. C, Balb/c generate a higher titer CRP-specific IgG than do C57Bl/6 mice in response to genetic immunization (p = 0.002). Each data point represents one mouse, data pooled from several individual experiments. Balb/c are represented by open squares, solid line; C57Bl/6 mice by closed circles, dashed line. * p<0.05, *** p<0.001 by Student's t test comparing Balb/c and C57Bl/6 models.