Table 2. Sensitivities of 3 NS1 antigen capture assays in patients with clinical diagnosis of acute dengue confirmed by RT-PCR and/or virus isolation and by MAC-ELISA.
NS1 antigen capture kitsNo. of sera with indicated result/total no. testeda | |||
Dengue case confirmation | pan-E DENGUE EARLY ELISA | Platelia™ Dengue NS1 Ag-ELISA | Dengue NS1 Ag STRIP |
RT-PCR only (n = 45) | 28/45 (62.3) | 37/45 (82.3) | 37/45 (82.3) |
Virus isolation only (n = 77) | 55/77 (71.5) | 73/77 (94.8) | 76/77 (98.7) |
RT-PCR and virus isolation (n = 36) | 33/36 (91.7) | 34/36 (94.5) | 36/36 (100) |
MAC-ELISA only | 43/62 (69.4) | 40/62 (64.5) | 48/62 (77.4) |
Total | 159/220 (72.3) | 184/220 (83.6) | 197/220 (89.6) |
Values in parentheses are percentages.