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. 2010 Jul 6;5(7):e11456. doi: 10.1371/journal.pone.0011456

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Song et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A): Increased Wnt/β-catenin activity in SP cells. SP and non-SP cells were transfected with TOPFLASH or FOPFLASH luciferase reporter assay. Relative luciferase activities were determined. (B): Endogenous Wnt target genes were highly expressed in SP cells. The expression of DKK1 and Axin2 was determined using Real-time RT-PCR. Relative mRNA expression levels were determined.