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Tumor formation by orthotopic inoculation. Mice were given bilateral intra-testicular injections of 2 × 106 JKT-1-C2-1 cells or mock-transfected JKT-1. JKT-1-C2-1 cells produced huge tumors extending to the retroperitoneal space, while mock transfectants produced small tumors (a, b). JKT-1-C2-1 cells also produced extensive mesenteric metastasis (arrows), while there were no such findings in mice inoculated with mock transfectants (c). Scale bar: 1 cm.
