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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Ann Hum Genet. 2010 May 31;74(4):351–360. doi: 10.1111/j.1469-1809.2010.00588.x

Table 3.

Type I error rates/powers for marker locus under additive mode of inheritance

T test T* test
Hypothesis 1 PS 2 PH 3 Empirical Asymptotic Empirical
Null Absent Absent 0.050 0.050 0.050
Null Absent Present 0.050 0.050 0.050
Null Present Absent 0.217 0.203 0.204
Null Present Present 0.885 0.876 0.876
Alternative Absent Absent 0.808 0.809 0.809
Alternative Absent Present 0.604 0.604 0.605
Alternative Present Absent 0.402 0.385 0.386
Alternative Present Present 0.153 0.142 0.143
1

“Null”: δ1 =δ2 = 0; “Alternative”: δ1 =δ2 = 0.05.

2

“Absent”: p1 = p2 = 0.2 and m1 = m2 = 0.3; “Present”: p1 = 0.1, p2 = 0.3 and m1 = 0.4, m2 = 0.2.

3

“Absent”: the penetrances of genotypes aa, Aa, AA are 0.1,0.2 and 0.3, respectively, in both of the subpopulations; “Present”: the penetrances are 0.1, 0.2 and 0.3 in subpopulation 1 and 0.2, 0.3 and 0.4 in subpopulation 2.