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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Psychoneuroendocrinology. 2009 Dec;34(Suppl 1):S143–S161. doi: 10.1016/j.psyneuen.2009.07.005

Diagram 1.

Diagram 1

Sources of 3α,5α-THP in the CNS include de novo biosynthesis in glial cells and metabolism of peripheral or central P.