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Anti-anxiety behavior on the elevated plus maze correlates with 3α,5α-THP in hippocampus of young (diestrous or proestrous), mid-aged (reproductively-competent or reproductively-senescent), or OVX (progesterone (P) with/without 3α,5α-THP inhibition, or 3α,5α-THP administration) rats. Bars represent open arm time (seconds±SEM) and dots represent 3α,5α-THP levels (ng/g±SEM) in hippocampus.
