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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Psychoneuroendocrinology. 2009 Dec;34(Suppl 1):S143–S161. doi: 10.1016/j.psyneuen.2009.07.005

Table 1.

Provides a break down of the timing, ligands, sources, and targets of steroid actions

Parameter Classic Steroid Action Neurosteroid Action
Timing Minutes, days, weeks Seconds to minutes
Ligands Progesterone (P), DHP 3α,5α-THP
Sources Ovaries, Adrenals Brain
Targets Intracellular PRs NT receptors, HPA