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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Nat Immunol. 2009 Sep 27;10(11):1178–1184. doi: 10.1038/ni.1791

Figure 8.

Figure 8

IL-10-producing CD11b+ myeloid cells prevent the downregulation of Foxp3. Flow cytometry of Foxp3 expression 3 weeks after the injection of 5 × 106 Rag1−/− or Il10−/−Rag1−/− intestinal CD11c+CD11b+F4/80+ cells (a) or CD11c+CD11bF4/80− cells (b) into Il10−/−Rag1−/− recipients, transferred intravenously on days 0 and 7 (where ‘day 0’ is the day of T cell transfer) with 4 × 105 CD4+ CD45RBhi (CD45.1+) cells in the presence of 1 × 105 (CD45.2+) Treg cells from Foxp3gfp mice. Plots are gated on TCRβ+CD4+CD45.2+ splenocytes. Data are representative of one of two independent experiments with a total of three mice.