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. Author manuscript; available in PMC: 2010 Jul 7.
Published in final edited form as: J Invest Dermatol. 2009 Aug 27;130(2):371–377. doi: 10.1038/jid.2009.252

Fig. 4. Restoration of abnormal epidermal differentiation and reduction of lymphocytes and leukocytes in K5.TGFβ1wt mice skin after short term Avandia@ treatment.

Fig. 4

(a) Staining of epidermal differentiation marker in K5.TGFβ1wt skin with and without Avandia@ treatment. Note that the loricrin and fillagrin lost in K5.TGFβ1wt skin reappeared (arrows) after 3 weeks Avandia@ treatment. (b) Short term Avandia@ treatment significantly reduced the infiltration of total leukocytes (CD45) and T lymphocytes (CD4), but not macrophages (BM8) in the skin from K5.TGFβ1wt mice. The bar in panel (a) and (b) represents 40μm.