FIG. 2.

Phylogenetic analysis of gag in ES8. Phylogenies were constructed as described for Fig. 1; ES8 is isolated due to the large number of sequences obtained for this patient. Colors indicate time, with the scale below in years. Triangles represent plasma sequences, squares represent proviral sequences from HLA-DR⁺ CD4⁺ T cells, and circles represent proviral sequences from HLA-DR⁻ CD4⁺ T cells. To the right, escape mutations in HLA B*57- and -B*27-restricted epitopes are denoted in black or gray and aligned with the appropriate symbol on the tree. Escape mutations are listed above the grid, with the epitopes in which the mutations occurred listed above the mutations.