FIG. 5.

Analysis of mutational load. The total number of point mutations per sequence from Vif ⁺ vector proviruses (A) or from Vif ⁻ vector proviruses (B) was determined in the HSA reporter gene region. Individual sequences are represented as filled gray circles. The black horizontal bar represents the average number of mutations identified per sequence. The data are a summary of sequence data of at least 50 independent proviral sequences from each cell line and from a total of three independent experiments. Identical mutants from the same PCR were only counted once.