FIG. 1.
Inhibition of IFN-β induction by different influenza A virus NS1 proteins. 293T cells were cotransfected for 16 h with a pCAGGS expression plasmid encoding the indicated NS1 protein (or GST) together with a FF-Luc IFN-β-promoter reporter plasmid (p125Luc). After infection with SeV for a further 12 h, FF-Luc activity was determined. The zoomed inset highlights differences between NS1 proteins. Results represent the means and standard deviations of triplicate values (normalized to GST plus SeV) obtained in a single experiment and are representative of results of two independent experiments.