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. Author manuscript; available in PMC: 2010 Jul 7.
Published in final edited form as: J Med Chem. 2008 Sep 24;51(20):6460–6470. doi: 10.1021/jm800692a

Figure 1.

Figure 1

(a) Synthesis of α,β-methylene-2’-deoxynucleoside 5’-triphosphates (α,β-m-dNTP, N= A, C, T, G)(12 – 15). (b) Formation of novel 2’-deoxycyclonucleosides (3,5’-cyclo-dG, 16 and 2,5’-cyclo-dT, 17)