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Western blot analysis of lamin A and lamin C expression in extracts from fibroblasts and mouse tissues. A, Western blots of extracts from Lmna+/+, LmnaLAO/LAO, and LmnaLAO/+ fibroblasts (two cell lines/genotype) with antibodies against lamin A/C, lamin B1, lamin B2, and actin. B–C, Western blots of heart and kidney extracts from Lmna+/+, LmnaLAO/LAO, and LmnaPLAO/PLAO mice (three mice/genotype) with antibodies against lamin A/C (panel B), mature lamin A (panel C), and actin.
