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. 2010 Apr 29;285(27):20716–20723. doi: 10.1074/jbc.M109.090845

FIGURE 3.

FIGURE 3.

Loss of adenosine receptors or ecto-5′-nucleotidase deficiency does not block DH by 5′-AMP. a, the VO2 profiles of ectonucleotidase/CD73-deficient (n = 2) and wild type mice following 5′-AMP (0.5 mg/g) administration. b, individual Tb of ectonucleotidase/CD73-deficient and wild type mice (n = 12) after 1 h at 4 °C Ta with injection of 0.125 mg/g 5′-AMP. c, top, Tb time course of mice (n = 4) with the adenosine receptor genotype A1−/−, A2a−/−, A2b−/−, or A3−/− or wild type were given 0.5 mg/g 5′-AMP after 1 h at 4 °C Ta. Bottom, Tb of mice of the same genotype given saline after 1 h at 4 °C Ta. Error bars, S.E.M.