TABLE 1.

Relative levels of purine intermediates in serum that showed significant alteration during euthermia, deep hypometabolism, arousal, and early recovery

For each group, the relative quantization value of each metabolite is the average obtained from seven mice. For each of the metabolites, the average euthermia control value is arbitrarily set at 1. The -fold change in DH, arousal, and early recovery is relative to the value obtained for euthermia. The probability that the changes were due to random factors is quantified by the p values, and the false positive rate is quantified by q values of t tests that are shown in italic type. (Note that for the data points with missing values, no acceptable measurement for that compound was obtained for the group.)

Altered purine metabolites (n = 7)	DH/Euthermia			Arousal/Euthermia			Early recovery/Euthermia
	-Fold change	p value	q value	-Fold change	p value	q value	-Fold change	p value	q value
Xanthine	8.83	0.000	0.001	4.97	0.012	0.007	1.13	0.356	0.127
Xanthosine	11.8	0.000	0.000	2.82	0.004	0.003	1.03	0.793	0.227
Hypoxanthine	8.69	0.004	0.005	3.07	0.033	0.017
Inosine	4.91	0.026	0.021	1.30	0.351	0.115
Adenosine	0.66	0.004	0.005	0.41	0.033	0.017	0.61	0.523	0.166
5′-AMP	1.21	0.026	0.021	1.44	0.351	0.115	0.92	0.587	0.178
ADP	1.79	0.021	0.019	2.02	0.004	0.003	0.95	0.807	0.228
Urate	3.3	0.001	0.001	2.70	0.002	0.002	1.57	0.144	0.064
Allantoin	15.3	0.000	0.000	18.16	0.000	0.000	13.44	0.000	0.000