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TMEM59 leads to retention of APP in the Golgi. HEK293 cells were transiently cotransfected with YFP-APP and either control plasmid (con)(A) or TMEM59 plasmid (B). The living cells were analyzed using a Zeiss 510Meta confocal system. The arrows point to the plasma membrane (red) and the Golgi (white), respectively. Scale bars = 10 μm.
