FIGURE 6.

Clinical significance of UCK1 and DGUOK expression in ERBB2-expressing breast cancer patients. Kaplan-Meier survival curves for breast cancer patients with high and low ERBB2 expression with respect to UCK1 (A) and DGUOK (B) expression. In the upper panels in A and B, Genome Institute of Singapore patient cohort data (38) were used. For lower panels, Jules Bordet Institute data (39) was used. High and low ERBB2 patients were determined from supplied ERBB2 measurement levels in the IJB clinical data. For the GIS data set, these were determined based on ERBB2 mRNA levels in the microarray dataset. p values were calculated using log-rank test in “survival” package for R. DGUOK, deoxyguanosine kinase.