TABLE 1.

Structural and functional parameters of the heart in 5-week-old SM22α-CreKI⁺/Klf4^loxP/loxP and control mice as measured by cardiac MRI

	SM22α-CreKI−Klf4loxP/loxP	SM22α-CreKI+Klf4loxP/loxP
Heart rate (beats/min)	441 ± 23	394 ± 25*
Left ventricular end diastolic volume (μl)	33.5 ± 1.8	33.8 ± 3.1
Left ventricular end systolic volume (μl)	11.5 ± 1.2	15.7 ± 1.9*
Stroke volume (μl)	22.0 ± 0.7	18.1 ± 1.6*
Ejection fraction (%)	66.2 ± 1.9	53.8 ± 2.6*
Cardiac output (μl/min)	9.7 ± 0.6	7.5 ± 0.2*
Left ventricular mass (mg)	43.0 ± 2.0	40.0 ± 2.3

*, p < 0.05 compared with SM22α-CreKI⁻/Klf4^loxP/loxP mice. n = 5 per each genotype.