TABLE 1.
Fluorescence-tagged CLDN protein association with CD81, Occludin, and CLDN1
| r2 (IQR)a | FIR (IQR) | %FRET ± S.D.b | |
|---|---|---|---|
| CD81 association with | |||
| CLDN1 | 0.5 (0.42–0.61) | 0.7 (0.67–0.74) | 60 ± 4 |
| CLDN4 | 0.2 (0.17–0.24) | 0.3 (0.21–0.41) | 5 ± 8 |
| CLDN6 | 0.6 (0.54–0.62) | 1.0 (0.80–1.10) | 50 ± 6 |
| CLDN7 | 0.0 (0.00–0.09) | NDc | ND |
| CLDN9 | 0.4 (0.36–0.50) | 0.5 (0.40–0.67) | 63 ± 7 |
| CLDN11 | 0.2 (0.16–0.23) | 0.3 (0.19–0.41) | 7 ± 4 |
| CLDN12 | 0.4 (0.28–0.48) | 0.5 (0.26–0.83) | 15 ± 12 |
| CLDN15 | 0.0 (0.00–0.04) | ND | ND |
| CLDN17 | 0.2 (0.17–0.30) | 0.3 (0.22–0.52) | 6 ± 8 |
| Occludin association with | |||
| CLDN1 | 0.4 (0.29–0.54) | 0.7 (0.60–0.82) | 48 ± 1 |
| CLDN4 | 0.2 (0.14–0.34) | 0.3 (0.29–0.53) | 30 ± 7 |
| CLDN6 | 0.2 (0.04–0.36) | 0.8 (0.57–0.53) | 27 ± 9 |
| CLDN7 | 0.1 (0.04–0.18) | ND | ND |
| CLDN9 | 0.3 (0.13–0.48) | 0.7 (0.39–0.79) | 18 ± 8 |
| CLDN11 | 0.4 (0.12–0.45) | 0.7 (0.62–0.83) | 23 ± 7 |
| CLDN12 | 0.3 (0.19–0.37) | 0.6 (0.51–0.71) | 38 ± 6 |
| CLDN15 | 0.1 (0.08–0.21) | ND | ND |
| CLDN17 | 0.5 (0.28–0.51) | 0.9 (0.74–1.07) | 40 ± 5 |
| CLDN1 association with | |||
| CLDN1 | 0.7 (0.67–0.74) | 0.5 (0.43–0.58) | 41 ± 4 |
| CLDN4 | 0.3 (0.22–0.41) | 0.2 (0.18–0.24) | 18 ± 12 |
| CLDN6 | 1.0 (0.82–1.11) | 0.6 (0.51–0.59) | 31 ± 6 |
| CLDN7 | 0.1 (0.00–0.10) | ND | ND |
| CLDN9 | 0.4 (0.36–0.42) | 0.5 (0.44–0.63) | 18 ± 3 |
a Interquartile range.
b Standard deviation.
c ND, not determined.