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cPLA2−/− MEFs are responsive to exogenous interferon. cPLA2+/+ and cPLA2−/− MEFs were treated with 100 units/ml IFN-γ and tested for the expression of IRG proteins (A) and the ability contain chlamydial replication, as assessed by the yield of infectious units (B). Note that both wild-type and cPLA2−/− MEFs express IRGs and contain C. trachomatis replication. Error bars indicate one standard deviation from the mean.
