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. 2010 May 4;285(28):21526–21536. doi: 10.1074/jbc.M110.129999

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© 2010 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 2. — Defective EC patterning within FAK^R454/R454 embryos. Whole embryos at E9.5 were stained with anti-CD31 to visualize ECs. Comparisons are between FAK^WT/WT and FAK^R454/R454 littermates. Defined EC branchlike and tubule structures (arrows) in the head and heart of FAK^WT/WT embryos are shown. FAK^R454/R454 embryos exhibit intense EC staining in the unfused allantois. Clusters (arrowheads) of ECs are present in FAK^R454/R454 head and heart structures, but these were not organized within a defined network.