TABLE 2.
Potassium chloride | Cortisol | Rapamycin | |
---|---|---|---|
Brefeldin A | No inhibitiona | No inhibition | No inhibition |
Pertussis toxin | No inhibition | No inhibition | No inhibition |
mPKI | 100% inhibition | 100% Inhibition | 100% Inhibition |
Akt inhibitor IV | No inhibition | No inhibition | 100% Inhibition |
PD 98059 | No inhibition | No inhibition | 90% Inhibition |
U72122 | No inhibition | No inhibition | No inhibition |
Mifepristone | No inhibition | 98% Inhibition | Not done |
3-Methyladenine | Not done | 95% Inhibition | 95–98% Inhibition |
a No inhibition indicates that the endozepine detected was indistinguishable from maximal level of 80 pmol/mg of protein, whereas 100% inhibition indicates the activity was under the detection limit of 0.5 pmol of endozepine/mg of protein.