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A proposed model for the stereopreference of TeSADH I86A following Prelog’s rule for predicting the stereopreference of alcohol dehydrogenases. The mutation I86A allows large substituents to fit into the large pocket of I86A TeSADH, which corresponds to the small pocket in wild-type TeSADH. ADPR, adenosine diphosphoribose. This figure was adapted from Musa et al. (2009 ▶).
