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. Author manuscript; available in PMC: 2010 Jul 7.
Published in final edited form as: J Immunol. 2010 May 17;184(12):6622–6628. doi: 10.4049/jimmunol.0902765

Figure 2. IgG from individual VT+/PM− patients but not VT−/PM+ promotes phosphorylation of NFκB and p38MAPK in U937 cells.

Figure 2

U937 cells were treated with purified IgG (100μg/ml) from seven individual patients chosen at random from four clinical groups (VT+/PM−, VT+/PM+, VT−/PM+, aPL+/APS−) or purified IgG (100μg/ml) from four healthy controls (aPL-negative) or TNFα (100ng/ml) for 6 hours. Quantitative analysis with antibodies specific for human phosphorylated and total proteins are shown against: - (A) NFκB p65 and (B) p38MAPK. Each value in the scattered plot of the quantitative analysis represents the mean of three experiments performed independently of each other. Statistically significant differences are shown (*p<0.05).