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. Author manuscript; available in PMC: 2010 Jul 7.
Published in final edited form as: Curr Opin Drug Discov Devel. 2010 Jan;13(1):66–77.

Figure 3.

Figure 3

Structures of anti-HIV protease inhibitors that irreversibly inhibit CYP3A4 via an MI complex formation. The arrows indicate sites of metabolism for known circulating metabolites (Table 2).