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. 2010 Mar 30;3(7-8):451–458. doi: 10.1242/dmm.003186

Fig. 6.

Fig. 6.

Osteoclast number and function. (A) There is no significant difference in the number of osteoclasts in fracture calluses of Ccr2−/− mice and wild-type mice at day 21, and (B) the differentiation of osteoclasts in vitro is not altered in the mutants. (C,D)Micrographs of the pits created in discs by wild-type (C) and mutant (D) osteoclasts. (E,F) Ccr2−/− osteoclasts create smaller numbers of larger pits (E) and resorb less surface area (F) in vitro than wild-type osteoclasts. MNC refers to multinucleated cells. *P<0.05, **P<0.01.