Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 May 18;3(7-8):486–495. doi: 10.1242/dmm.004390

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. 1. — oliver mutants show a liver-specific phenotype. (A) Bright-field images of 6-dpf Tg(–2.8fabp10:EGFP)^as3WT (top) and oli^s469 mutant (bottom) larvae combined with fluorescence to reveal their liver (arrows). By 6 dpf, and compared with their WT siblings, oli^s469 mutants (bottom) exhibit an o-shaped liver of reduced size (arrow) in an otherwise phenotypically WT body. (B,C) Confocal images of 5-dpf Tg(–2.8fabp10:EGFP)^as3WT (B) and oli^s469 mutant (C) livers stained with phalloidin (red) and TO-PRO (blue). EGFP expression (green) in hepatocytes reveals a well-organized structure in the WT liver, contrasting with the disarray observed in oli^s469 mutants. (D,E) Confocal images of 5-dpf Tg(fabp10:RFP)^gz12WT (D) and oli^s469 mutant (E) livers stained for cadherin (green) and TO-PRO (blue). The cells surrounded by the few hepatocytes (red) that are detected in oli^s469 mutant livers express cadherin (green) at levels that, at this stage in WT livers, are characteristic of cells of the intrahepatic biliary tree (D, arrows). Bars, 20 μm.